Laboratory of Clinical Research coordinates clinical studies and clinical trials of drugs conducted at the National Research Center for Pediatric Oncology, Hematology and Immunology, sorts out issues of improving the diagnosis and treatment of children and adolescents with cancer, primary immune deficiencies and blood disorders.
The Molecular Genetic Laboratory is a clinical diagnostic facility specializing in oncologic molecular testing.Also we provide laboratory research related to the diagnostic and study of childhood cancer. Our laboratory provide the identification of genes involved in cancer and leukaemia predisposition, development and progression, as well as molecular diagnosis to detect cancer and predict drug response and resistance.
Laboratory cellular bioengineering (biotechnology) and cytotherapy was established in National Research Centre for Pediatric Oncology, Hematology and Immunology in 2011. Investigations for adoption of new technology in clinic practice are led by the instrumentality of hemopoietic and nonhemopoietic cells in case cancer (oncological), haematological patients or somatic disease.
Research connected with development of anticancer DNA-vaccine has been initiated in the laboratory. In the frames of this work molecular cloning of tumor associated antigens (TAA), stimulatory and immunogenic proteins is performed. Experimental mouse model is developing for the assessment of vaccines’ therapeutic efficiency.
One of the priority directions of scientific activity is to create a mathematical model for the recognition of a situation in which the possible development of thrombosis or bleeding in children and adults stages of chemotherapy, patients with tumors and hematological malignancies.
Laboratory of Immunological Research of the Republican Scientific and Practical Center of Pediatric Oncology, Hematology and Immunology